DEAD box proteins are involved in an assortment of metabolic processes that typically involve RNAs, but in some cases also other nucleic acids. [2] They are highly conserved in nine motifs …

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DEAD-box helicases are a large family of conserved RNA-binding proteins that belong to the broader group of cellular DExD/H helicases. Members of the DEAD-box helicase family have …

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Jun 19, 2025 · DEAD-box RNA helicases play vital roles in every aspect of RNA metabolism, from transcriptional regulation to translation initiation. Altered expression levels and mutations in …

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Apr 15, 2021 · DEAD-box proteins, named for the amino acid sequence of a tremendously conserved motif (Asp-Glu-Ala-Asp [D-E-A-D]), constitute the largest family of RNA helicases, …

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Mar 1, 2004 · DEAD-box proteins use the energy from ATP hydrolysis to rearrange inter- or intra-molecular RNA structures or dissociate RNA–protein complexes. Such dynamic …