Heliot Ramos, Rafael Devers and Wilmer Flores homered off Nestor Cortes in the first inning and the San Francisco Giants beat San Diego 4-3 to hand the Padres their fourth straight loss.

Petco Park’s packed house filled the Gaslamp Quarter with a symphony of boos. Ramos proceeded to troll the Padres fans sitting in the left-field bleachers, pointing and laughing at the Friar faithful. The rest of the night, Ramos was greeted with boos every time he stepped to the plate or fielded a fly ball.

Wilmer Flores' two-run shot capped a three-homer first inning for the visiting Giants and Robbie Ray fired 6 2/3 solid innings in San Francisco's 4-3 victory over the San Diego Padres on Monday.

The San Francisco Giants got their daunting road trip off to a strong start with a 4-3 win against the San Diego Padres on Monday at Petco Park.

San Diego Padres center fielder Jackson Merrill is out of the Padres lineup against the Giants on Monday after suffering an apparent left ankle injury in Sunday's series finale against the Dodgers.

Jackson Merrill slugged his ninth home run of the season in the eighth inning to put the finishing touches on the Giants (59-61) defeat. San Diego improved to 68-52 and pulled into a tie with the Dodgers for first place in the NL West.