The Detroit Lions lost for the first time since Sept. 15 in a high-scoring affair with the Buffalo Bills in Week 15 at Ford Field in Detroit in a matchup of two of the NFL's best teams. The Lions (12-1) fell into an early two-touchdown hole and could not ...

Winning 11 straight games in the NFL — the Detroit Lions’ current streak — is pretty rare. But winning 12 straight, as the Lions could do on Sunday with a victory over the Buffalo Bills at Ford Field (4:25 p.m., CBS)? That’s elite territory ...

Detroit — The Buffalo Bills defeated the Detroit Lions 48-42 Sunday at Ford Field in Detroit. This game was an offensive battle from start to finish. The teams combined for 1088 yards of offense ...

The Bills improved to 11-3, two games behind the Kansas City Chiefs in the AFC with three games remaining, and took a one-game lead over Pittsburgh for the conference’s second seed.

but he’s a powerful edge-setter against the run and the Lions must make the Bills one-dimensional on offense by stopping James Cook and the running game. Buffalo averages 6.47 yards per carry ...

Kickoff is on Sunday, Dec. 15, at 4:25 p.m. ET on CBS. The Detroit Lions will host the Buffalo Bills at Ford Field for a highly anticipated game.

Here’s the preview, odds, best bets, and expert predictions for the upcoming Buffalo Bills vs. Detroit Lions game.

The second game is the best of the three. The Cincinnati Bengals are a 3-point favorite against the Denver Broncos. The Bengals need to win and then hope to get help to make the playoffs, but they're alive and presumably we'll get their best effort. The Bengals will be a popular side.

The order of the teams that secured their place in the NFL postseason has yet to be defined, but the first favorites in the AFC and NFC are already emerging.