Carlos Alcaraz has a strong chance to reclaim the ATP No.1 ranking after the US Open 2025, with a title or deep run enough to overtake Jannik Sinner. Alcaraz had held the top spot in the rankings back in 2022 as a 19-year-old.

Sabalenka is currently +285 to repeat as champion, second only to Iga Swiatek at +240. Sinner, meanwhile is favored to repeat at +110, slightly ahead of rival Carlos Alcaraz at +175. With some of those odds in mind, let's take a look at some of the best betting options to consider in both the men's and women's tournaments this year in New York.

Jannik Sinner has received a brutal reality check as he prepares to defend his title at the US Open. The world No. 1 recently lifted his fourth Grand Slam trophy at Wimbledon, beating Carlos Alcaraz in the final. If he can retain his crown in Flushing Meadows, he’ll tie Alcaraz on five Majors.