Researchers identified LENG8 as a key RNA quality control protein that prevents defective RNA from leaving the nucleus. By ...

When a gene is expressed, its DNA sequence is transcribed into a molecule known as RNA. Then the cell processes and edits that RNA before it is translated into protein. Many genes can be processed and ...

How do cells ensure that the "blueprints" of genetic information-RNA are accurate and intact before they are exported from ...

Biology textbooks explain that cells follow a universal rule when processing gene transcripts to make proteins. Non-coding snippets of RNA are bracketed by a guanine-thymine (GT) nucleotide sequence ...

The field of RNA-targeted therapeutics is rapidly evolving, offering groundbreaking opportunities for the treatment of a wide array of diseases ...

The IDR in TAF2 steers the protein away from active gene promoters, where it participates in transcription initiation, to nuclear speckles — liquid-like compartments that concentrate factors for RNA ...

Cancers driven by hiccups in RNA processing can’t hide from our immune system, according to new work published today in Cell. A cross-institutional team Fred Hutch Cancer Center and Memorial Sloan ...

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other ...

v. 1. Synthesis and purification of RNA substrates / Benoit Chabot -- Characterization of RNA / Paula J. Grabowski -- Splicing of mRNA precursors in mammalian cells / Ian C. Eperon, Adrian R. Krainer ...