Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...

Figure 1. Flowchart of the working principle of machine learning based on single-round nucleic acid aptamer screening sequences, including: deep learning of core sequences, machine learning analysis ...

This schematic shows the secondary structure of two aptamers. The complex shapes formed by base pairing (black lines connecting G-C and A-T bases) allow aptamers to bind their targets with high ...

DNA and RNA are central to laboratory and clinical research, where quantifying their abundance is key to applications such as gene expression analysis, cell and gene therapy development, and ...

When James Watson and Francis Crick described the double-helix structure of DNA in 1953, the moment appeared decisive and complete. Yet that breakthrough rested on work carried out decades earlier by ...