Predictions, picks and odds for NFL Week 2 game
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Total: NBC Sports is staying away from a play on the Total of 46.5.
The Detroit Lions and the Buffalo Bills meet Thursday for their Week 2 game in Orchard Park, New York. Kickoff is scheduled for 8:15 p.m. ET.
We asked our NFL analysts and reporters to make predictions for the 2026 season. Who are their favorites to win the Super Bowl and the MVP award?
Total: NBC Sports is leaning towards a play on the Total UNDER 41.5.