Our bodies contain immune cells called macrophages. Normally, these cells attack and suppress bacteria and cancer cells.

CAR-T cell therapies have fundamentally transformed the treatment of several blood and lymph node cancers. However, their use in solid tumors such as liver, breast or lung cancer has so far been ...

A new review maps the engineering strategies, from dual-target receptors to tumor microenvironment remodeling, that could ...

New MSK studies reveal that immune cells secretly feed triple-negative breast cancer, a CXCR2 blocker sensitizes leptomeningeal metastases to radiation, ERBB2 mutations predict enhanced benefit from ...

High-risk MDS stem cells appear to have an unexpected “energy addiction,” relying far more heavily than healthy blood-forming cells on a molecule called NAD. Disrupting this energy pathway selectively ...

Researchers at Hokkaido University, in collaboration with an international team of scientists led by the University of South ...

CAF Crosstalk to Reprogram the tumor microenvironment (TME). Ctx-ETAC suppresses EV secretion, disrupts cancer-CAF ...

Scientists at UC San Francisco have developed a way to create cancer-fighting CAR-T cells directly inside the body, potentially avoiding the slow and extremely expensive process of removing, ...

Scientists identified a driver of aggressive prostate cancer and a potential way to stop drug-resistant tumors forming.

Scientists from A*STAR Institute of Molecular and Cell Biology (A*STAR IMCB) have identified the specific cells responsible for gastric cancer's tendency to return after treatment. The study also ...