The proteins of the Bcl-2 family are key players in the mitochondrial pathway of apoptosis. They form a complex interaction network that determines the permeabilization of the mitochondrial outer ...
B-cell lymphoma 2 (Bcl-2)-associated X protein (Bax) is a member of the Bcl-2 protein family having a pivotal role in triggering cell commitment to apoptosis. Bax is latent and monomeric in the ...
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