A-kinase anchoring proteins (AKAPs) target protein kinase A (PKA) to distinct subcellular locations. This positions the enzyme at regions of cyclic-AMP production and confines phosphorylation to a ...
Figure 1: Characterization of AKAP-Lbc–KSR-1 interactions. We have evaluated how AKAP-Lbc shapes ERK signalling through its interaction with KSR-1. The convergence of AKAP-Lbc and KSR-1 binding ...
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